
Maximize Dairy Cow Performance with BioCycle® Plus
Integrates the benefits and ingredients of BioCycle® and DTX™ with powerful L-form bacteria to tackle mold-driven issues, ensuring effective reproduction, production, and health.

DEFEND & PROTECT
Dual-Action Protection
BioCycle® Plus is a direct-fed microbial supplement formulated to support the digestive and immune systems of dairy cattle. Designed for professional dairy nutrition programs, it combines the benefits of BioCycle® and DTX™ with powerful L-form bacteria to help herds manage stress, combat mold-driven challenges, and maintain consistent health, reproduction, and production. Also available with Non-GMO ingredients.
THE GOLD STANDARD OF HEALTHY HERDS.
Unlock the Potential of Your Dairy Herd
Stronger Heat Expression
Field reports show stronger heat expression within 3-4 weeks of feeding, leading to improved conception rates.
Stabilize Feed Intake
Helps stabilize feed intake within two weeks, ensuring consistent nutrient absorption and better overall health.
Research & Resources
BioCycle® Plus products contains the DTX™ Technology
PRODUCT DETAILS
Ingredients & Guidelines
Contains a source of Amylase to hydrolyze starch, Protease for hydrolyzing proteins, Cellulase for breaking down cellulose, Hemicellulase for breaking down Hemicellulose, and a source of live (viable) naturally occuring microorganisms, and organic acids for cattle.
On-Farm Mixing
Select BioCycle® Plus

Use Directions
Mix Select BioCycle® Plus into manufactured feeds at the rate of:
- Beef and dairy heifers: 7 g/head/d (0.25 oz)
- Dry and lactating cows: Recommended 14 g/head/d (0.50 oz)
Fungal amylase (A. oryzae) 7,000 SKB/g
Fungal protease (A. oryzae) 5,000 HUT/g
Lipase (Candida cylindracea) 500 FIP/g
Cellulase (T. reesei) 5,000 CU/g
Pectinase (A. niger) 100 ENDO-PG/g
Total microbial activity
(Bacillus subtilis, Lactobacillus acidophilus) (min) 60 x 106 cfu/g
Ingredients
Montmorillonite clay, calcium carbonate, silicon dioxide, Saccharomyces cerevisiae (active dry yeast), yeast culture, rosemary, sugars, naringin, malic acid, turmeric, potassium iodide, dried egg product, dried Aspergillus oryzae fermentation extract, propionic acid, dried Bacillus subtilis fermentation product, dried Lactobacillus acidophilus fermentation product, tartaric acid, lactic acid, citric acid, aspartic acid.
Packaging & Storage
Select BioCycle® Plus is available in 50lb. boxes. Store in a cool, dry place to maintain its efficacy for up to two years.
Feed Mill Mixing
BioCycle® Plus Concentrate

Use Directions
Mix BioCycle® Plus Concentrate into mixed feeds at the rate of:
-
- Beef and dairy heifers: 5 g/head/d (0.18 oz)
- Dry and lactating cows: Recommended 10 g/head/d (0.35 oz)
Fungal amylase (A. oryzae) 7,000 SKB/g
Fungal protease (A. oryzae) 5,000 HUT/g
Lipase (Candida cylindracea) 500 FIP/g
Cellulase (T. reesei) 5,000 CU/g
Pectinase (A. niger) 100 ENDO-PG/g
Total microbial activity
(Bacillus subtilis, Lactobacillus acidophilus) (min) 60 x 106cfu/g
Ingredients
Montmorillonite clay, calcium carbonate, silicon dioxide, Saccharomyces cerevisiae (active dry yeast), yeast culture, rosemary, sugars, naringin, malic acid, turmeric, potassium iodide, dried egg product, dried Aspergillus oryzae fermentation extract, propionic acid, dried Bacillus subtilis fermentation product, dried Lactobacillus acidophilus fermentation product, tartaric acid, lactic acid, citric acid, aspartic acid.
Packaging & Storage
BioCycle® Plus Concentrate is available in 50lb. bags. Store in a cool, dry place to maintain its efficacy for up to two years.

A Complete Approach to Feed Hygiene and Herd Performance Challenges
Defending and protecting cattle against feed hygiene challenges involves two categories of feed additives: binders or probiotic products. Independent, peer-reviewed research indicates that clay and yeast cell wall products are ineffective at “binding” mycotoxins and might actually be more efficacious for binding nutrients, and thereby reducing nutrient bioavailability¹,².
BioCycle® Plus product combines the benefits of BioCycle® and DTX™ for cattle facing multiple challenges of feed hygiene, digestive pathogens, heat, and other factors. BioCycle Plus®, a direct-fed microbial product, features L-form or cell wall-deficient bacteria (CWDB). Independent, peer-reviewed research with the CWDB found improved milk production and reproductive success when lactating dairy cows were challenged by DON and zearalenone³,⁴. The BioCycle® Plus also features a proprietary blend of natural plant actives sourced from turmeric, naringin, and rosemary to defend intestinal integrity and protect liver health for the next level in mycotoxin protection.
¹Kihal et al. (2022). J. Anim. Sci. 100:1-14.
²Kihal et al. (2020). J. Dairy Sci. 103:3125-3132.
³Roth et al. (2024). J. Dairy Sci. 107(Suppl 1):426 (Abstr.).
⁴Roth et al. (2024). J. Dairy Sci. 107(Suppl 1):426 (Abstr.).

Real Results
“There are many products on the market; I believe BioCycle® Plus is the most effective product to actually solve the problem, instead of just putting a band-aid on it. It’s effective during times of high stress, such as the warmest days of the year; when a significant feed change happens; or anytime toxins are present in the feed. Time and again, I’ve seen it work on customer farms as effectively as any feed additive. Comments continually roll in that milk pounds came up or failed to dip in the heat or during a feed change; SCC decreased across the herd and especially on trouble cows; conception rates increase; and heats are stronger.”
“After 60 days of feeding Select BioCycle® Plus all 30 of my bulls passed their breeding soundness exam (BSE). In the past, I would have 5-10% that didn’t pass. That wasn’t the case this year. I can confidently say this is the best ROI I’ve ever made!”
“We started an embryo transfer business and needed to give donor cows the best chance of success. Feeding BioCycle® Plus has done that. Cows respond with increased amounts and improved quality of transferred embryos. The results have been remarkable.”
The Agrarian Difference

Broad Spectrum Mycotoxin Protection
L-form bacteria protect against digestive damage without binding essential nutrients.

Supports Reproductive Performance
Helps maintain fertility and stronger heat expression despite toxin exposure.

Enhances Immune Response
Strengthens gut and liver function to minimize the negative effects of mycotoxins.

Improves Feed Efficiency
Maximizes nutrient absorption even in mycotoxin-challenged diets.

Get Started with Select BioCycle® Plus
Select BioCycle® Plus is available through one of our designated distributors. Find a distributor near you.

Learn More About BioCycle® Plus Concentrate
DTX™ Concentrate • BioCycle® Concentrate • BioCycle® Plus Concentrate are available direct from Agrarian Solutions.
